ZIETZSCHMANN-PREUSS AWARD

2023: Martine VAN DEN BROECK (Laboratory of Veterinary Morphology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium) for the paper entitled: “Time and sequence of emergence of the deciduous dentition in dogs and its applicability for age estimation” in co-authorship with L. De Bels, L. Duchateau and P. Cornillie and published in the Journal Anatomia Embryologia Histologia, 2022, 51:640-657.

The investigation by the authors comprises a longitudinal study in very extensive number of pups of a vast amount of dog breeds, covering all breeds sizes and types, of age related changes to the deciduous dentition, which undoubtedly form solid reference material for the currently highly relevant topic of age assessment in growing dogs.

2022: Javad SADEGHINEZHAD (Department of Basic Sciences, Faculty of Veterinary Medicine, University of Teheran, Iran) for the paper entitled: “Morphometric study of the testis in sheep embryos using unbiased design-based stereology” in co-authorship with Z. Ganji, S.S. Chaleshtori, H. Bojarzadeh, M.A. Asl, A.B. Khomejini, E. Roominai, M. Hosseini and M. De Silva and published in the Journal Anatomia Histologia Embryologia 2021, 50:1026-1033.

The prize-winning paper was commended for its clear and unbiased approach, providing useful data on the development of ovine testes that are compared with the development in the human and as such can serve as a model for translational research.

2021: Christina Alexandra KALENBERG (Division of Veterinary Anatomy, University of Bern, Länggassstrasse 120, 3001 Bern, Switzerland) for the paper entitled “The embryonic development of the bovine stomach revisited” in co-authorship with M.H. Stoffel and published in the Journal Anatomia Histologia Embryologia 2020, 49:270-280.

The paper is a very comprehensive and well-illustrated micro-anatomical and ultrastructural developmental study on the altering layout of the bovine forestomachs in the 26-80 days old embryo. The authors are praised for turning their extensive research into a very didactic paper with clear images and elaborate descriptions.

2020: Miguelangel Moncayo-Donoso (Biometrics Laboratory and Numerical Methods Modeling Research Group, Instituto de Biotecnologia, Universidad Nacional de Colombia, Bogotá, Colombia) for the paper entitled: “Morphological changes of physeal cartilage and secondary ossification centres in the developing femur of the house mouse (Mus musculus): A micro‐CT based study” in co-authorship with J.M. Guevara, K. Márquez-Flórez, M.R. Fontanilla, L.A. Barrera and D.A. Garzón-Alvarado and published in the Journal Anatomia Histologia Embryologia 2019, 48:117-124.

This paper was applauded for using state-of-the-art imaging and computational morphometric analysis of the pre- and postnatal developmental changes in the shape and composition of the murine femur, providing new insights in the ossification and growth patterns of developing bone.

2019: Daniela Rodler (Department of Veterinary Sciences, Ludwig-Maximilian University of Munich, Munich, Germany) for the paper entitled: “Localization of thrombospondin-1 and its receptor CD36 in the ovary of the ostrich (Struthio camelus)” in co-authorship with F. Sinowatz and published in the Journal Anatomia Histologia Embryologia 2018, 47:124-132.

The Zietzschmann‐Preuss award’s board of trustees valued the paper for its in-depth analysis and correlation of the immunohistochemical localization of anti-angiogenic factors with morphological features at the ultramicroscopical level.

2018: Miriam Beyes (Institute of Veterinary Medicine, Georg-August-Universität, Göttingen, Germany) for the paper entitled: “Description of post-implantation embryonic stages in European roe deer (Capreolus capreolus) after embryonic diapause” in co-authorship with N. Nause, M. Bleyer, F.-J. Kaup and S. Neumann and published in the Journal Anatomia Histologia Embryologia 2017, 46:582-591.

The board of trustees of the Zietzschmann-Preuss award valued the paper for its clear and comprehensive illustration of the morphological characteristics of roe deer embryos at different stages of prenatal development and praised the authors for the contribution of novel findings that necessitate the re-evaluation of current scientific insights on timing and termination of embryonic diapause in this species.

2017: Bajram Berisha of the Faculty of Agriculture and Veterinary, University of Prishtina, Kosovo and Animal Physiology and Immunology Weihenstephan, Technical University of Munich, Germany, for his paper entitled: “Angiogenesis in The Ovary - The Most Important Regulatory Event for Follicle and Corpus Luteum Development and Function in Cow - An Overview. ”, in co-authorship with D. Schams, D. Rodler and M. W. Pfaffl and published in the Journal Anatomia Histologia Embryologia 2016, 45, pp. 124-130.

2016 : Claire Douart (Laboratory of Anatomy of Domestic Animals, Oniris, Nantes Atlantic National College of Veterinary Medicine, Anatomy of Domestic Animals, BP 40 706, Nantes cedex 3F, 44307 France) for her paper entitled: “Temporal Evolution of Hepatic Anatomy During Gestation and Growth in the Sheep” which she published, together with the co-authors L. Briand, E. Betti, D. Bencharif and D. Tainturier, in the Journal Anatomia Histologia Embryologia, 2015, 44, pp. 22-36.

2015 : Cordula GABRIEL (BARTEL) (Institute of Anatomy, Histology and Embryology, Department of Pathobiology, Veterinärplatz 1, A-1210 Vienna, Austria) for her paper entitled: “Characterization of Foamy Epithelial Surface Cells in the Canine Endometrium” which she published, together with the co-authors A. Tichy and I. Walter, in the Journal Anatomia Histologia Embryologia, 2014, 43, pp. 165-181.

This paper was elected and applauded as being an authentic, detailed, excellently illustrated microscopic study of the canine endometrium, which is based on a wide range of methods, contains interesting reflections on the potential role of this specific endometrial morphology in early pregnancy events, and is therefore clinically very relevant.

2014 : Barbara MAURER (Center for Anatomy and Cell Biology, Medical University of Vienna, Währingerstraße 13, A-1090 Vienna, Austria) for the paper entitled: “A Chick Embryo with a yet Unclassified Type of Cephalothoracopagus Malformation and a Hypothesis for Explaining its Genesis”, which she published, together with the co-authors S.H. Geyer and W.J. Weninger, in the Journal Anatomia Histologia Embryologia, 2013, 42, pp. 191-200.

The prize has been awarded because this paper because it contains a challenging novel hypothesis, based on impressive three-dimensional and quantification techniques, and resulting in a classical embryological study with excellent illustrations combined with a modern and promising point of view.

2013 : Monica COLITTI (Department of Agricultural and Environmental Sciences, Via delle Scienze 206, 33100 Udine, Italy) for the paper entitled: “BCL-2 Family of Proteins and Mammary Cellular Fate” published in the Journal Anatomia Histologia Embryologia, 2012, 41, pp. 237-247. This paper was awarded as a very nice, thorough review of the pro-apoptotic and anti-apoptotic Bcl-2 family members, presenting innovative aspects of applied research and showing how the mammary gland can serve as a model tissue to study the regulation of cellular fate.

2012 : Tamas SOMFAI (National Institute of Livestock and Grassland Science, National Agriculture and Food Research Organization (NARO), 2 Ikenodai, Tsukuba, Ibaraki 905-0901, Japan) for his paper entitled: “Cytoskeletal Abnormalities in Relation with Meiotic Competence and Ageing in Porcine and Bovine Oocytes During in vitro Maturation”, which he published, together with co-authors K. Kikuchi, M. Kaneda, S. Akagi, S. Watanabe, E. Mizutani, S. Haraguchi, T. Q. Dang-Nguyen, Y. Inaba, M. Geshi and T. Nagai, in the Journal Anatomia Histologia Embryologia , 2011, 40, pp. 335-344.

This well documented and nicely illustrated study deals with an important topic and is based on the use of different morphological techniques. For a long time neglected, the cytoskeleton is more and more in the focus of modern research. The in vitro results of this study increase our knowledge of general principles as well as the species specificity of problems in assisted reproduction of domestic animals.

2011 : Ward DE SPIEGELAERE (Department of Morphology, Faculty of Veterinary Medicine, Salisburylaan 133, B-9820 Merelbeke, Ghent University, Belgium) for his paper entitled: “Detection of Hypoxia Inducible Factors and Angiogenic Growth Factors during Foetal Endochondral and Intramembranous Ossification” which he published, together with the co-authors P. Cornillie, C. Casteleyn, C. Burvenich and W. Van den Broeck, in the Journal Anatomia Histologia Embryologia, 2010, 39, pp. 376-384.

In their motivation, the Board Members applauded this paper as an excellent investigation which is based on a diverse methodological approach, offers important data for better understanding the complex topic of skeletogenesis, is concluded with a most interesting discussion, and has high potential clinical impact.

2010 : Sabine KAESSMEYER (Institute of Veterinary Anatomy, Faculty of Veterinary Medicine, Freie Universität Berlin, Koserstrasse 20, D-14195 Berlin, Deutschland) for her paper entitled: “New Insights in Vascular Development: Vasculogenesis and Endothelial Progenitor Cells” which she published together with J. Plendl, P. Custodis and M. Bahramsoltani in the Journal Anatomia Histologia Embryologia, 2009, 38, 1-11.

The prize has been awarded because this very well documented and illustrated paper gives an excellent review of vascular development, an item which has a major impact in prenatal organogenesis as well as in numerous normal and pathological postnatal processes. It offers very clear, well defined and precise insights, contains substantial contributions made by the research team of the authors, and presents a extensive reference list which is a most useful source of information.

2009 : Rebecca KENNGOTT (Lehrstuhl für Tieranatomie II, University of Munich, Veterinärstrasse 13, D-80539 Munich, Germany), for her paper entitled: "Expression and Distribution of Intermediate-filament Proteins and Laminin during the development of the Bovine Müllerian Duct”, that she published together with Prof. F. Sinowatz in the Journal Anatomia Histologia Embryologia, 2008, 37, 223-230.

The prize has been awarded because this immunohistochemical study, along with a number of other papers in which the laureate describes the prenatal development of the bovine oviduct, presents elaborate and abundantly documented information about the development of the mammalian female genital tract.

2008 : Giorgia CABIANCA (Department of Experimental Veterinary Science, University of Padua, Agripolis, Legnaro (PD), Italy) for her paper entitled "Expression of Anti Müllerian Hormone (AMH) in Female Fetal Intersex Gonads in the Bovine", which she published together with A. Rota, B. Cozzi and C. Ballarin in the Journal Anatomia Histologia Embryologia, 2007, 36, 24-26. The prize has been awarded because this clear and comprehensive immunohistochemical study presents interesting novel insights into the mechanisms causing bovine freemartinism, which is a phenomenon of major clinical relevance.

2007 : Tatsuya TADA (Laboratory of Animal Morphology and Function, Graduate School of Bioagricultural Science, Chikusa-ku, Nagoya, Japan) for his paper entitled "Morphological Study of the Transition of Haematopoietic Sites in the Developing Mouse During the Peri-natal Period" which he published together with D.T. WIDAYATI and K. FUKUTA in the Journal Anatomia Histologia Embryologia, 2006, 35, 235-240. The prize has been awarded to the Laureate because of the originality and thoroughness of his study, dealing with a most important period in haematopoiesis that had not received much attention hitherto.

2006 : Nagwa EL-NEFIAWY (Department of Anatomy and Embryology, Faculty of Medicine, Ain Shams University, Abassia, Cairo, Egypt) for her paper entitled "Dendritic Cell Differentiation and Maturation in Embryonic Rat Liver: Immunohistochemistry and Electron Microscopy with Reference to Dendritic Cell Contacts" which she published together with K. ABDEL-HAKIM, N. KANAYAMA and T. TERAO in the Journal Anatomia Histologia Embryologia, 2005, 34, 72-79.

2005 : Joo-Cheol PARK (Department of Oral Histology, College of Dentistry, Chosun University, Dong-Gu, Gwang-Ju, Korea) for his paper entitled: "Preferential Expression of L-type Amino Acid Transporter 1 in Ameloblasts During Rat Tooth Development" which he published together with Y. B. KIM, J. H. YOON, H.-J. KIM, S. M. KIM, Y. KANAI, H. ENDOU and D. K. KIM, in the Journal Anatomia Histologia Embryologia, 2004, 33, 119-124.

The prize-paper has been recommended as a most important immunohistochemical study of dental development which opens new perspectives for better understanding odontogenesis, presenting novel and well documented data resulting from a modern investigation.

2004 : Deryl L. TROYER (Department of Anatomy and Physiology, Kansas State University, Manhattan, USA) for his paper entitled: "Incorporation of Bovine Bone Marrow Stromal Cells into Porcine Foetal Tissues after Xenotransplantation" which he published, together with M.L. WEISS, K.E. MITCHELL, P.L.MARTIN and D.L. DAVIS, in the Journal Anatomia Histologia Embryologia, 32, 98-101, 2003. This paper describes an animal model for the introduction and integration of autologous stem cells into foetal organs, and provides an important potential for ex-vivo gene therapy to enhance the health and well-being of animals and humans.

2003 : Fred SINOWATZ (Institute of Veterinary Anatomy, University of Munich, Germany) for his extensive and excellent work on veterinary embryology, as evidenced by numerous publications in scientific books and journals, and in particular for his paper entitled: "Functional Morphology of the Zona Pellucida" which he published, together with E. TÖPFER-PETERSEN, S. KÖLLE and G. PALMA, in the Journal Anatomia Histologia Embryologia, 30, 257-26, 2001.

This paper reviews a functionally important topic of reproduction in a very clear and precise style and with excellent illustrations, and perfectly illustrates that the Laureate is a leading scientist in the area of veterinary reproduction and embryology.

2002 : Katja PRELLE (Ludwig Maximilian University Munich, Germany) for her paper entitled "Immunocytochemical Analysis of Vimentin Expression Patterns in Porcine Embryos Suggests Mesodermal Differentation from Day 9 After Conception" which she published together with W. HOLTZ and M.OSBORN in the journal Anatomia Histologia Embryologia, 30, 339-344, 2001.

This study offers new insight into inner cell mass differentiation in a most important experimental animal species by using modern techniques. The excellent scientific merits of the laureate are further evidenced by the very informative review paper on pluripotent embryonic stem cells published by the same author in a subsequent issue of Anatomia Histologia Embryologia, 31, 169-186, 2002.

2001 : Ahmet K. KARABULUT (Selcuk University, Konya, Turkey) for his paper entitled "Growth-Promoting Effects of Different Fractions of Extra-Embryonic Coelomic Fluid on Embryonic Development", published together with R. LAYFIELD and M. K. PRATTEN in the journal Anatomia, Histologia, Embryologia, 29, 225 -234, 2000.

This experimental embryologic study makes use of a wide range of modern techniques and a nice iconography for demonstrating the presence of growth-promoting factors that regulate embryonic development. This well documented paper offers a useful model for further basic and applied research in laboratory and domestic animal development.

2000 : Katrin HENNEICKE - URBAN (University of Hannover, Germany) for her studies published together with M. HEWICKER- TRAUTWEIN and G. TRAUTWEIN, "Development of Myelination in the Bovine Fetal Brain: an Immunohistochemical Study" (Anat. Histol. Embryol. 26, 187-193, 1997) and "Immunohistochemical Localization of Transferrin in the Pre- and Postnatal Bovine Brain" (Anat. Histol. Embryol. 27, 45-49, 1998).

The exact knowledge of the pre- and postnatal development of the brain is very important for understanding various hereditary and congenital diseases of the nervous system in the ox. However, the number of fundamental studies dealing with the ontogenesis of the bovine brain is still amazingly small. The thorough immunohistochemical investigations by K. Urban, M. Hewicker- Trautwein and G. Trautwein have broadened our insight into the normal progress of myelination in the central nervous system, and the localization of transferrin in the oligodendrocytes during ontogenesis is a very important contribution to understanding of this process. Therefore these studies contain most interesting and useful information about the development of the bovine brain.

1999 : Brigitte M. GRETHER (University of Bern, Switzerland) for her paper entitled "The Glandular Changes of the Placenta of the Bitch in the Second Third of Pregnancy (day 30-40): An Ultrastructural, Ultrachemical and Lectinhistochemical Investigation", which she published together with A.E. Friess and M.H. Stoffel in the Journal Anatomia, Histologia, Embryologia,1998, 27, 95-103.

This meticulous paper, which is an elaboration of the dissertation study of the senior author, is based on an excellent methodology and contains important original findings and excellent illustrations. This investigation forms an important progress in the study of placental function.

1998 : Gerhard HUMMEL (Justus-Liebig-University Giessen, Germany) for his study "Development, Cytoarchitecture and Ultrastructure of the Mesencephalic Trigeminal Nucleus in Domestic Ruminants" (Anat. Histol. Ernbryol. 26, 99-106, 1997) which he wrote with A. HILD and S. WENISCH, as well as for his further fundamental investigations of the mesencephalon and other parts of animal brains, including in part embryology. Hummel's publications are based on subtle working on extensive material. The morphological results are always interpreted functionally. The award of the Otto Zietzschmann Prize should also be a recognition for the many years of neuroanatomical research by the laureate.

1997 : Eduardo MARTIN (University of Montevideo, Uruguay) for his study "Development of the Genital Peritoneal Folds in Mammals" (Anat.Histol.Embryol. 22, 201-211, 1993; 24, 285-287, 1995; 25, 187-195,1996).

As first and only author the prizewinner investigated basic questions of homology and described the species-specific characteristics of the development of the genital folds in sheep and pig. The studies are documented exemplarily and carry on the basic thoughts of O. Zietzschmann to a scientifically and didactically important result. His study is a step forward of education and research in veterinary embryology.

1996 : Clemens KNOSPE (University of München, Germany) for his studies "Zur praenatalen Entwicklung des Pferdeovars" (Anat.Histol.Embryol. 21, 306-313, 1992) and "Zur praenatalen Entwicklung der Glandula mandibularis und Glandula parotis der Katze" (Anat.Histol.Embryol. 24, 1-6, 1995). These papers excell by a precise methodology and clear descriptions.

Furthermore, Prof. Knospe has published - either a sole author or together with various co-authors- a series of important and original studies on veterinary embryology which give proof of his expertise in experimental veterinary embryological research and will promote the further development of this field of reach. Awarding the Otto Zietzschmann Prize to Prof. Knospe is both an acknowledgment and a support for his in-depth investigations.

1995: Tosiro TIBA (University of Gifu, Japan) for his study "Regularities and Irregularities in the Structure of the Seminiferous Epithelium in the Domestic Fowl (Gallus domesticus)" (Anat. Histol. Embryol. 21, 241-253 and 254-263, 1993). Dr. T. TIBA and his colleagues K. YOSHIDA, M. MIYAKE, Y.S. SHIMIZU, K. TSUCHIYA, I. KITA and T. TSUBOTA have succeeded very well in giving a clear and detailed description of spermatogenesis in birds. He has inaugurated a topic of high scientific topicality, and has investigated it meticulously with exemplary documentation. His study is a step forward in reproductive biology and veterinary embryology.